CK1δ-Derived Peptides as Novel Tools Inhibiting the Interactions between CK1δ and APP695 to Modulate the Pathogenic Metabolism of APP

CK1δ-Derived Peptides as Novel Tools Inhibiting the Interactions between CK1δ and APP695 to Modulate the Pathogenic Metabolism of APP

Alzheimer’s disease (AD) is the major cause of dementia, and affected individuals suffer from severe cognitive, mental, and functional impairment. Histologically, AD brains are basically characterized by the presence of amyloid plaques and neurofibrillary tangles. Previous reports demonstrated that...

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Bibliographic Details
Main Authors: Aileen Roth, Fabian Gärtner, Katja Mayer, Julian Beyrle, Irina König, Uwe Knippschild, Joachim Bischof
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
AD
casein kinase 1
CK1
amyloid precursor protein
APP
Online Access:https://www.mdpi.com/1422-0067/22/12/6423

Internet

https://www.mdpi.com/1422-0067/22/12/6423

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