Tumor-associated macrophages in tumor metastasis: biological roles and clinical therapeutic applications

Abstract Tumor metastasis is a major contributor to the death of cancer patients. It is driven not only by the intrinsic alterations in tumor cells, but also by the implicated cross-talk between cancer cells and their altered microenvironment components. Tumor-associated macrophages (TAMs) are the k...

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Bibliographic Details
Main Authors: Yuxin Lin, Jianxin Xu, Huiyin Lan
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Journal of Hematology & Oncology
Subjects:
TME
Online Access:http://link.springer.com/article/10.1186/s13045-019-0760-3