Exosomal MicroRNA-126 from RIPC Serum Is Involved in Hypoxia Tolerance in SH-SY5Y Cells by Downregulating DNMT3B

Exosomal MicroRNA-126 from RIPC Serum Is Involved in Hypoxia Tolerance in SH-SY5Y Cells by Downregulating DNMT3B

Ischemic tolerance in the brain can be induced by transient limb ischemia, and this phenomenon is termed remote ischemic preconditioning (RIPC). It still remains elusive how this transfer of tolerance occurs. Exosomes can cross the blood-brain barrier, and some molecules may transfer neuroprotective...

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Bibliographic Details
Main Authors: Junhe Cui, Na Liu, Zhehan Chang, Yongsheng Gao, Mulan Bao, Yabin Xie, Wenqiang Xu, Xiaolei Liu, Shuyuan Jiang, You Liu, Rui Shi, Wei Xie, Xiaoe Jia, Jinghua Shi, Changhong Ren, Kerui Gong, Chunyang Zhang, Rengui Bade, Guo Shao, Xunming Ji
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
remote ischemic preconditioning
microRNA-126
exosome
DNA methyltransferase 3B
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120301165

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http://www.sciencedirect.com/science/article/pii/S2162253120301165

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