Preferential expression of cytochrome CYP CYP2R1 but not CYP1B1 in human cord blood hematopoietic stem and progenitor cells

Preferential expression of cytochrome CYP CYP2R1 but not CYP1B1 in human cord blood hematopoietic stem and progenitor cells

Cytochrome P450 (CYP) enzymes metabolize numerous endogenous substrates, such as retinoids, androgens, estrogens and vitamin D, that can modulate important cellular processes, including proliferation, differentiation and apoptosis. The aim of this study is to characterize the expression of CYP genes...

Full description

Bibliographic Details
Main Authors: Shuoqi Xu, Zhihua Ren, Yanan Wang, Xinxin Ding, Yongping Jiang
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Cytochrome P450
CYP2R1
CYP1B1
CD34+
Hematopoietic stem cells
Gene expression
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383514001026

Internet

http://www.sciencedirect.com/science/article/pii/S2211383514001026

Similar Items