An autoinhibitory clamp of actin assembly constrains and directs synaptic endocytosis

Synaptic membrane-remodeling events such as endocytosis require force-generating actin assembly. The endocytic machinery that regulates these actin and membrane dynamics localizes at high concentrations to large areas of the presynaptic membrane, but actin assembly and productive endocytosis are far...

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Bibliographic Details
Main Authors: Steven J Del Signore, Charlotte F Kelley, Emily M Messelaar, Tania Lemos, Michelle F Marchan, Biljana Ermanoska, Markus Mund, Thomas G Fai, Marko Kaksonen, Avital Adah Rodal
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/69597