Intra-tumor heterogeneity in breast cancer has limited impact on transcriptomic-based molecular profiling

Intra-tumor heterogeneity in breast cancer has limited impact on transcriptomic-based molecular profiling

Abstract Background Transcriptomic profiling of breast tumors provides opportunity for subtyping and molecular-based patient stratification. In diagnostic applications the specimen profiled should be representative of the expression profile of the whole tumor and ideally capture properties of the mo...

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Bibliographic Details
Main Authors: Govindasamy-Muralidharan Karthik, Mattias Rantalainen, Gustav Stålhammar, John Lövrot, Ikram Ullah, Amjad Alkodsi, Ran Ma, Lena Wedlund, Johan Lindberg, Jan Frisell, Jonas Bergh, Johan Hartman
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Cancer
Subjects:
Breast cancer
Molecular diagnostics
Molecular subtypes
Intra-tumor transcriptomic heterogeneity
Online Access:http://link.springer.com/article/10.1186/s12885-017-3815-2

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http://link.springer.com/article/10.1186/s12885-017-3815-2

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