Cellular Stress and p53-Associated Apoptosis by Juniperus communis L. Berry Extract Treatment in the Human SH-SY5Y Neuroblastoma Cells

Cellular Stress and p53-Associated Apoptosis by Juniperus communis L. Berry Extract Treatment in the Human SH-SY5Y Neuroblastoma Cells

Plant phenolics have shown to activate apoptotic cell death in different tumourigenic cell lines. In this study, we evaluated the effects of juniper berry extract (Juniperus communis L.) on p53 protein, gene expression and DNA fragmentation in human neuroblastoma SH-SY5Y cells. In addition, we analy...

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Bibliographic Details
Main Authors: Tiina A. Lantto, Into Laakso, H. J. Damien Dorman, Timo Mauriala, Raimo Hiltunen, Sulev Kõks, Atso Raasmaja
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:International Journal of Molecular Sciences
Subjects:
apoptosis
Juniperus communis L.
plant extract
ER stress
p53
SH-SY5Y neuroblastoma cells
Online Access:http://www.mdpi.com/1422-0067/17/7/1113

Internet

http://www.mdpi.com/1422-0067/17/7/1113

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