Myosin 1E localizes to actin polymerization sites in lamellipodia, affecting actin dynamics and adhesion formation

Summary Because the actin network in active lamellipodia is continuously assembling at the edge, moving inward and disassembling, there is a question as to how actin-binding proteins and other components are transported to the leading edge and how nascent adhesions are stabilized. Active transport c...

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Bibliographic Details
Main Authors: Prabuddha Gupta, Nils C. Gauthier, Yu Cheng-Han, Yuan Zuanning, Bruno Pontes, Malte Ohmstede, René Martin, Hans-Joachim Knölker, Hans-Günther Döbereiner, Mira Krendel, Michael Sheetz
Format: Article
Language:English
Published: The Company of Biologists 2013-10-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/2/12/1288