Mapping Tyrosine Kinase Receptor Dimerization to Receptor Expression and Ligand Affinities

Tyrosine kinase receptor (RTK) ligation and dimerization is a key mechanism for translating external cell stimuli into internal signaling events. This process is critical to several key cell and physiological processes, such as in angiogenesis and embryogenesis, among others. While modulating RTK ac...

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Bibliographic Details
Main Authors: Spencer B. Mamer, Alexandra A. Palasz, P. I. Imoukhuede
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Processes
Subjects:
Online Access:https://www.mdpi.com/2227-9717/7/5/288