Long reads reveal the diversification and dynamics of CRISPR reservoir in microbiomes

Abstract Background Sequencing of microbiomes has accelerated the characterization of the diversity of CRISPR-Cas immune systems. However, the utilization of next generation short read sequences for the characterization of CRISPR-Cas dynamics remains limited due to the repetitive nature of CRISPR ar...

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Bibliographic Details
Main Authors: Tony J. Lam, Yuzhen Ye
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-019-5922-8