Probing relevant molecules in modulating the neurite outgrowth of hippocampal neurons on substrates of different stiffness.

Hippocampal neurons play a critical role in learning and memory; however, the effects of environmental mechanical forces on neurite extension and associated underlying mechanisms are largely unexplored, possibly due to difficulties in maintaining central nervous system neurons. Neuron adhesion, neur...

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Bibliographic Details
Main Authors: Wei-Hsin Chen, Sin-Jhong Cheng, Jason T C Tzen, Chao-Min Cheng, Yi-Wen Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3875460?pdf=render