Up-regulated Dicer expression in patients with cutaneous melanoma.

BACKGROUND: MicroRNAs (miRNAs) are small non-coding RNAs (18-24 nucleotides) that have recently been shown to regulate gene expression during cancer progression. Dicer, a central enzyme in the multi-component miRNA biogenesis pathway, is involved in cutting precursor miRNAs to functionally mature fo...

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Bibliographic Details
Main Authors: Zhihai Ma, Helen Swede, David Cassarino, Elizabeth Fleming, Andrew Fire, Soheil S Dadras
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3117784?pdf=render