Dehydroepiandrosterone-Regulated Testosterone Biosynthesis via Activation of the ERK1/2 Signaling Pathway in Primary Rat Leydig Cells

Dehydroepiandrosterone-Regulated Testosterone Biosynthesis via Activation of the ERK1/2 Signaling Pathway in Primary Rat Leydig Cells

Background: Dehydroepiandrosterone decreases with age and this reduction has been shown to be associated with physical health in human. Some studies have suggested that the effects of DHEA are exerted after it is biotransformed into more biologically-active hormones in peripheral target cells. This...

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Bibliographic Details
Main Authors: Lin Liu, Jian Kang, Xiao Ding, Di Chen, Yingqiao Zhou, Haitian Ma
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Dehydroepiandrosterone
Testosterone biosynthesis
ERK signaling pathway
Primary Leydig cell
Online Access:http://www.karger.com/Article/FullText/430150

Internet

http://www.karger.com/Article/FullText/430150

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