Galectin-1 and galectin-3 as key molecules for peripheral nerve degeneration and regeneration

Galectin-1 and galectin-3 as key molecules for peripheral nerve degeneration and regeneration

There is growing evidence that galectin-1 (GAL-1) and galectin-3 (GAL-3) are involved in the process of axonal regeneration after injury and the pathogenesis of peripheral neuropathies, but the precise roles of these galectins in the peripheral nervous system (PNS) remain unclear. In this paper, we...

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Bibliographic Details
Main Authors: Hideji Yako, Hidenori Horie, Kazunori Sango, Kunihiko Sakumi, Masami Tsukamoto, Naoko Niimi, Toshihiko Kadoya, Yusaku Nakabeppu, Shizuka Takaku
Format: Article
Language:English
Published: AIMS Press 2016-07-01
Series:AIMS Molecular Science
Subjects:
galectin-1
galectin-3
dorsal root ganglion neurons
Schwann cells
macrophages
Wallerian degeneration
axonal regeneration
glial cell line-derived neurotrophic factor (GDNF)
diabetic neuropathy
Online Access:http://www.aimspress.com/Molecular/article/852/fulltext.html

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