Methylome Dynamics of Bovine Gametes and in vivo Early Embryos

Methylome Dynamics of Bovine Gametes and in vivo Early Embryos

DNA methylation undergoes drastic fluctuation during early mammalian embryogenesis. The dynamics of global DNA methylation in bovine embryos, however, have mostly been studied by immunostaining. We adopted the whole genome bisulfite sequencing (WGBS) method to characterize stage-specific genome-wide...

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Bibliographic Details
Main Authors: Jingyue Ellie Duan, Zongliang Carl Jiang, Fahad Alqahtani, Ion Mandoiu, Hong Dong, Xinbao Zheng, Sadie L. Marjani, Jingbo Chen, Xiuchun Cindy Tian
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Genetics
Subjects:
DNA methylation
gametes
single early embryo
WGBS
bovine
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00512/full

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https://www.frontiersin.org/article/10.3389/fgene.2019.00512/full

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