Mass Cytometry Studies of Patients With Autoimmune Endocrine Diseases Reveal Distinct Disease-Specific Alterations in Immune Cell Subsets

Mass Cytometry Studies of Patients With Autoimmune Endocrine Diseases Reveal Distinct Disease-Specific Alterations in Immune Cell Subsets

Although there is evidence that autoimmune diseases share similar immunogenetic mechanisms, studies comparing peripheral CD45+ cells from patients with autoimmune endocrine diseases in parallel are limited. In this study, we applied high-dimensional single-cell mass cytometry to phenotypically chara...

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Bibliographic Details
Main Authors: Louise Magnusson, Hugo Barcenilla, Mikael Pihl, Sophie Bensing, Daniel Espes, Per-Ola Carlsson, Rosaura Casas
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
mass cytometry (CyTOF)
type 1 diabetes
Hashimoto's thyroiditis
Graves' disease
Addison's disease
antigen-presenting cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00288/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00288/full

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