Pathogenesis of Target Organ Damage in Hypertension: Role of Mitochondrial Oxidative Stress

Pathogenesis of Target Organ Damage in Hypertension: Role of Mitochondrial Oxidative Stress

Hypertension causes target organ damage (TOD) that involves vasculature, heart, brain and kidneys. Complex biochemical, hormonal and hemodynamic mechanisms are involved in the pathogenesis of TOD. Common to all these processes is an increased bioavailability of reactive oxygen species (ROS). Both i...

Full description

Bibliographic Details
Main Authors: Speranza Rubattu, Beniamino Pagliaro, Giorgia Pierelli, Caterina Santolamazza, Sara Di Castro, Silvia Mennuni, Massimo Volpe
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:International Journal of Molecular Sciences
Subjects:
target organ damage
hypertension
mitochondrial dysfunction
oxidative stress
Online Access:http://www.mdpi.com/1422-0067/16/1/823

Internet

http://www.mdpi.com/1422-0067/16/1/823

Similar Items