The Effect of MGCD0103 on CYP450 Isoforms Activity of Rats by Cocktail Method

MGCD0103, an isotype-selective histone deacetylase inhibitor (HDACi), has been clinically evaluated for the treatment of hematologic malignancies and advanced solid tumors, alone and in combination with standard-of-care agents. In order to investigate the effects of MGCD0103 on the metabolic capacit...

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Bibliographic Details
Main Authors: Jinzhang Cai, Qingwei Zhang, Kezhi Lin, Lufeng Hu, Yuancai Zheng
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/517295