The Effect of MGCD0103 on CYP450 Isoforms Activity of Rats by Cocktail Method

The Effect of MGCD0103 on CYP450 Isoforms Activity of Rats by Cocktail Method

MGCD0103, an isotype-selective histone deacetylase inhibitor (HDACi), has been clinically evaluated for the treatment of hematologic malignancies and advanced solid tumors, alone and in combination with standard-of-care agents. In order to investigate the effects of MGCD0103 on the metabolic capacit...

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Bibliographic Details
Main Authors:	Jinzhang Cai, Qingwei Zhang, Kezhi Lin, Lufeng Hu, Yuancai Zheng
Format:	Article
Language:	English
Published:	Hindawi Limited 2015-01-01
Series:	BioMed Research International
Online Access:	http://dx.doi.org/10.1155/2015/517295

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