Calsequestrin-1 Regulates Store-Operated Ca2+ Entry by Inhibiting STIM1 Aggregation

Calsequestrin-1 Regulates Store-Operated Ca2+ Entry by Inhibiting STIM1 Aggregation

Background/Aims: Stromal interacting molecule-1 (STIM1) aggregation and redistribution to plasma membrane to interact with Orai1 constitute the core mechanism of store-operated Ca2+ entry (SOCE). Previous study has revealed that calsequestrin-1 (CSQ1) regulates SOCE in HEK293 cells through interacti...

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Bibliographic Details
Main Authors: Lane Zhang, Limin Wang, Shu Li, Jingyi Xue, Dali Luo
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
CSQ1
STIM1
Orai1
SOCE
STIM1 Aggregation
Online Access:http://www.karger.com/Article/FullText/445574

Internet

http://www.karger.com/Article/FullText/445574

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