Scalable Biomimetic Coaxial Aligned Nanofiber Cardiac Patch: A Potential Model for “Clinical Trials in a Dish”

Scalable Biomimetic Coaxial Aligned Nanofiber Cardiac Patch: A Potential Model for “Clinical Trials in a Dish”

Recent advances in cardiac tissue engineering have shown that human induced-pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) cultured in a three-dimensional (3D) micro-environment exhibit superior physiological characteristics compared with their two-dimensional (2D) counterparts. These 3D c...

Full description

Bibliographic Details
Main Authors: Naresh Kumar, Divya Sridharan, Arunkumar Palaniappan, Julie A. Dougherty, Andras Czirok, Dona Greta Isai, Muhamad Mergaye, Mark G. Angelos, Heather M. Powell, Mahmood Khan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
nanofibers
cardiac patch
myocardial infarction
cardiovascular disease
multielectrode array (MEA)
3D model
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.567842/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.567842/full

Similar Items