Sustained IGF-1 Secretion by Adipose-Derived Stem Cells Improves Infarcted Heart Function

Sustained IGF-1 Secretion by Adipose-Derived Stem Cells Improves Infarcted Heart Function

The mechanism by which stem cell-based therapy improves heart function is still unknown, but paracrine mechanisms seem to be involved. Adipose-derived stem cells (ADSCs) secrete several factors, including insulin-like growth factor-1 (IGF-1), which may contribute to myocardial regeneration. Our aim...

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Bibliographic Details
Main Authors: Luiza L. Bagno, Deivid Carvalho, Fernanda Mesquita, Ruy A. Louzada, Bruno Andrade, Taís H. Kasai-Brunswick, Vivian M. Lago, Grazielle Suhet, Debora Cipitelli, João Pedro Werneck-De-Castro, Antonio C. Campos-De-Carvalho
Format: Article
Language:English
Published: SAGE Publishing 2016-09-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368915X690215

Internet

https://doi.org/10.3727/096368915X690215

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