Comparative Analysis of Global Proteome and Lysine Acetylome Between Naive CD4+ T Cells and CD4+ T Follicular Helper Cells

Comparative Analysis of Global Proteome and Lysine Acetylome Between Naive CD4+ T Cells and CD4+ T Follicular Helper Cells

As a subgroup of CD4+ T helper cells, follicular helper T (Tfh) cells provide help to germinal center B cells and mediate the development of long-lived humoral immunity. Dysregulation of Tfh cells is associated with several major autoimmune diseases. Although recent studies showed that Tfh cell diff...

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Bibliographic Details
Main Authors: Ming Zhao, Sujie Jia, Xiaofei Gao, Hong Qiu, Ruifang Wu, Haijing Wu, Qianjin Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
lysine acetylation
histone acetyltransferases
histone deacetylases
follicular helper T cell
proteome
acetylome
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.643441/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.643441/full

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