Current View in Platinum Drug Mechanisms of Peripheral Neurotoxicity
Peripheral neurotoxicity is the dose-limiting factor for clinical use of platinum derivatives, a class of anticancer drugs which includes cisplatin, carboplatin, and oxaliplatin. In particular cisplatin and oxaliplatin induce a severe peripheral neurotoxicity while carboplatin is less neurotoxic. Th...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-08-01
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Series: | Toxics |
Subjects: | |
Online Access: | http://www.mdpi.com/2305-6304/3/3/304 |