Effect of CAR activation on selected metabolic pathways in normal and hyperlipidemic mouse livers

<p>Abstract</p> <p>Background</p> <p>Detoxification in the liver involves activation of nuclear receptors, such as the constitutive androstane receptor (CAR), which regulate downstream genes of xenobiotic metabolism. Frequently, the metabolism of endobiotics is also mod...

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Bibliographic Details
Main Authors: Björkhem Ingemar, Lövgren-Sandblom Anita, Tamasi Viola, Režen Tadeja, Meyer Urs A, Rozman Damjana
Format: Article
Language:English
Published: BMC 2009-08-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/10/384