Association of ABCC8 and KCNJ11 gene variants with type 1 diabetes in south Indians

Association of ABCC8 and KCNJ11 gene variants with type 1 diabetes in south Indians

Abstract Background Type 1 diabetes mellitus (TIDM) is a polygenic disorder with the involvement of several genetic and environmental risk factors. Mutation in genes namely ABCC8 and KCNJ11 disrupt the potentiality of KATP channel and regulates the secretion of insulin by detecting a change in the b...

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Bibliographic Details
Main Authors: Shilpa Reddy, Sailaja Maddhuri, Pratibha Nallari, Venkateshwari Ananthapur, Srinivas Kalyani, Murali Krishna, Nirmala Cherkuri, Sireesha Patibandala
Format: Article
Language:English
Published: SpringerOpen 2021-04-01
Series:Egyptian Journal of Medical Human Genetics
Subjects:
Type 1 diabetes
KATP channel
ABCC8 gene
KCNJ11gene
Insulin
MODY
Online Access:https://doi.org/10.1186/s43042-021-00149-w

Internet

https://doi.org/10.1186/s43042-021-00149-w

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