Antipruritic Effect of Nalbuphine, a Kappa Opioid Receptor Agonist, in Mice: A Pan Antipruritic

Antipruritic Effect of Nalbuphine, a Kappa Opioid Receptor Agonist, in Mice: A Pan Antipruritic

Antipruritic effects of kappa opioid receptor (KOR) agonists have been shown in rodent models of acute and chronic scratching (itchlike behavior). Three KOR agonists, nalfurafine, difelikefalin, and nalbuphine, are in clinical studies for antipruritic effects in chronic itch of systemic and skin dis...

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Bibliographic Details
Main Authors: Saadet Inan, Nae J. Dun, Alan Cowan
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
nalbuphine
kappa opioid receptor agonist
pruritis
scratching
mice
TAT-HIV
Online Access:https://www.mdpi.com/1420-3049/26/18/5517

Internet

https://www.mdpi.com/1420-3049/26/18/5517

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