Non-coding and Coding Transcriptional Profiles Are Significantly Altered in Pediatric Retinoblastoma Tumors

Non-coding and Coding Transcriptional Profiles Are Significantly Altered in Pediatric Retinoblastoma Tumors

Retinoblastoma is a rare pediatric tumor of the retina, caused by the homozygous loss of the Retinoblastoma 1 (RB1) tumor suppressor gene. Previous microarray studies have identified changes in the expression profiles of coding genes; however, our understanding of how non-coding genes change in this...

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Bibliographic Details
Main Authors: Swetha Rajasekaran, Lakshmi Dhevi Nagarajha Selvan, Kathleen Dotts, Ranjith Kumar, Pukhraj Rishi, Vikas Khetan, Madhoolika Bisht, Karthikeyan Sivaraman, Subrmanian Krishnakumar, Debashis Sahoo, Moray J. Campbell, Sailaja V. Elchuri, Wayne O. Miles
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Oncology
Subjects:
retinoblastoma
LNC-RNAs
RNA-sequencing
LNC targeting
DRAIC
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00221/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.00221/full

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