Obesity-Induced Dysbiosis Exacerbates IFN-γ Production and Pulmonary Inflammation in the <i>Mycobacterium tuberculosis</i> Infection

Obesity-Induced Dysbiosis Exacerbates IFN-γ Production and Pulmonary Inflammation in the <i>Mycobacterium tuberculosis</i> Infection

The microbiota of the gut–lung axis affects local and far-reaching immune responses and might also trigger chronic and inflammatory diseases. We hypothesized that gut dysbiosis induced by obesity, which coexists in countries with a high tuberculosis burden, aggravates the host susceptibility and the...

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Bibliographic Details
Main Authors: Sandra Patricia Palma Albornoz, Thais Fernanda de Campos Fraga-Silva, Ana Flávia Gembre, Rômulo Silva de Oliveira, Fernanda Mesquita de Souza, Tamara Silva Rodrigues, Isis do Carmo Kettelhut, Camila Sanches Manca, Alceu Afonso Jordao, Leandra Naira Zambelli Ramalho, Paulo Eduardo Martins Ribolla, Daniela Carlos, Vânia Luiza Deperon Bonato
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
gut–lung axis
microbiota
obesity
tuberculosis
Online Access:https://www.mdpi.com/2073-4409/10/7/1732

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https://www.mdpi.com/2073-4409/10/7/1732

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