Extracellular Vesicles From Liver Progenitor Cells Downregulates Fibroblast Metabolic Activity and Increase the Expression of Immune-Response Related Molecules

Extracellular Vesicles From Liver Progenitor Cells Downregulates Fibroblast Metabolic Activity and Increase the Expression of Immune-Response Related Molecules

Extracellular vesicles (EVs) mediate cell-to-cell crosstalk whose content can induce changes in acceptor cells and their microenvironment. MLP29 cells are mouse liver progenitor cells that release EVs loaded with signaling cues that could affect cell fate. In the current work, we incubated 3T3-L1 mo...

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Bibliographic Details
Main Authors: Felix Royo, Mikel Azkargorta, Jose L. Lavin, Marc Clos-Garcia, Ana R. Cortazar, Monika Gonzalez-Lopez, Laura Barcena, Hernando A. del Portillo, María Yáñez-Mó, Antonio Marcilla, Francesc E. Borras, Hector Peinado, Isabel Guerrero, Mar Váles-Gómez, Unai Cereijo, Teresa Sardon, Ana M. Aransay, Felix Elortza, Juan M. Falcon-Perez
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
extracellular vesicles (EVs)
exosomes
MLP29
fibroblast
cell crosstalk
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.613583/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.613583/full

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