Critical role of bacterial dissemination in an infant rabbit model of bacillary dysentery

The bacterial pathogen Shigella flexneri causes bacillary dysentery (bloody diarrhoea). Here, Yum et al. present an infant rabbit model of S. flexneri infection that recapitulates human disease symptoms and features bacterial dissemination as an essential determinant of pathogenesis.

Bibliographic Details
Main Authors: Lauren K. Yum, Mariana X. Byndloss, Sanford H. Feldman, Hervé Agaisse
Format: Article
Language:English
Published: Nature Publishing Group 2019-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09808-4