Critical role of bacterial dissemination in an infant rabbit model of bacillary dysentery

Critical role of bacterial dissemination in an infant rabbit model of bacillary dysentery

The bacterial pathogen Shigella flexneri causes bacillary dysentery (bloody diarrhoea). Here, Yum et al. present an infant rabbit model of S. flexneri infection that recapitulates human disease symptoms and features bacterial dissemination as an essential determinant of pathogenesis.

Bibliographic Details
Main Authors: Lauren K. Yum, Mariana X. Byndloss, Sanford H. Feldman, Hervé Agaisse
Format: Article
Language:English
Published: Nature Publishing Group 2019-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09808-4
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spelling doaj-c499ad32f62d4286a31b88f1da55b0bd2021-05-11T12:21:12ZengNature Publishing GroupNature Communications2041-17232019-04-0110111010.1038/s41467-019-09808-4Critical role of bacterial dissemination in an infant rabbit model of bacillary dysenteryLauren K. Yum0Mariana X. Byndloss1Sanford H. Feldman2Hervé Agaisse3Department of Microbiology, Immunology, and Cancer Biology, University of VirginiaDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical CenterCenter for Comparative Medicine, University of VirginiaDepartment of Microbiology, Immunology, and Cancer Biology, University of VirginiaThe bacterial pathogen Shigella flexneri causes bacillary dysentery (bloody diarrhoea). Here, Yum et al. present an infant rabbit model of S. flexneri infection that recapitulates human disease symptoms and features bacterial dissemination as an essential determinant of pathogenesis.https://doi.org/10.1038/s41467-019-09808-4
collection DOAJ
language English
format Article
sources DOAJ
author Lauren K. Yum
Mariana X. Byndloss
Sanford H. Feldman
Hervé Agaisse
spellingShingle Lauren K. Yum
Mariana X. Byndloss
Sanford H. Feldman
Hervé Agaisse
Critical role of bacterial dissemination in an infant rabbit model of bacillary dysentery
Nature Communications
author_facet Lauren K. Yum
Mariana X. Byndloss
Sanford H. Feldman
Hervé Agaisse
author_sort Lauren K. Yum
title Critical role of bacterial dissemination in an infant rabbit model of bacillary dysentery
title_short Critical role of bacterial dissemination in an infant rabbit model of bacillary dysentery
title_full Critical role of bacterial dissemination in an infant rabbit model of bacillary dysentery
title_fullStr Critical role of bacterial dissemination in an infant rabbit model of bacillary dysentery
title_full_unstemmed Critical role of bacterial dissemination in an infant rabbit model of bacillary dysentery
title_sort critical role of bacterial dissemination in an infant rabbit model of bacillary dysentery
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2019-04-01
description The bacterial pathogen Shigella flexneri causes bacillary dysentery (bloody diarrhoea). Here, Yum et al. present an infant rabbit model of S. flexneri infection that recapitulates human disease symptoms and features bacterial dissemination as an essential determinant of pathogenesis.
url https://doi.org/10.1038/s41467-019-09808-4
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AT sanfordhfeldman criticalroleofbacterialdisseminationinaninfantrabbitmodelofbacillarydysentery
AT herveagaisse criticalroleofbacterialdisseminationinaninfantrabbitmodelofbacillarydysentery
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