Kinetics of Fluorescein in Tear Film After Eye Drop Instillation in Beagle Dogs: Does Size Really Matter?

The study aimed to determine the impact of drop size on tear film pharmacokinetics and assess important physiological parameters associated with ocular drug delivery in dogs. Two separate experiments were conducted in eight healthy Beagle dogs: (i) Instillation of one drop (35 μl) or two drops (70 μ...

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Bibliographic Details
Main Authors: Lionel Sebbag, Nicolette S. Kirner, Rachel A. Allbaugh, Alysha Reis, Jonathan P. Mochel
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Veterinary Science
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fvets.2019.00457/full