Blood Group Antigen Recognition via the Group A Streptococcal M Protein Mediates Host Colonization

Streptococcus pyogenes (group A streptococcus [GAS]) is responsible for over 500,000 deaths worldwide each year. The highly virulent M1T1 GAS clone is one of the most frequently isolated serotypes from streptococcal pharyngitis and invasive disease. The oral epithelial tract is a niche highly abunda...

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Main Authors: David M. P. De Oliveira, Lauren Hartley-Tassell, Arun Everest-Dass, Christopher J. Day, Rebecca A. Dabbs, Thomas Ve, Bostjan Kobe, Victor Nizet, Nicolle H. Packer, Mark J. Walker, Michael P. Jennings, Martina L. Sanderson-Smith, Anders P. Hakansson, Larry S. McDaniel
Format: Article
Language:English
Published: American Society for Microbiology 2017-01-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/1/e02237-16