Glycogen synthase kinase 3, circadian rhythms, and bipolar disorder: a molecular link in the therapeutic action of lithium

Glycogen synthase kinase 3, circadian rhythms, and bipolar disorder: a molecular link in the therapeutic action of lithium

<p>Abstract</p> <p>Background</p> <p>Bipolar disorder (BPD) is a widespread condition characterized by recurring states of mania and depression. Lithium, a direct inhibitor of glycogen synthase kinase 3 (GSK3) activity, and a mainstay in BPD therapeutics, has been propo...

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Bibliographic Details
Main Authors: Woodgett James R, Anthopoulos Norman, Doble Brad, Kaladchibachi Sevag A, Manoukian Armen S
Format: Article
Language:English
Published: Ubiquity Press 2007-02-01
Series:Journal of Circadian Rhythms
Online Access:http://www.jcircadianrhythms.com/content/5/1/3

Internet

http://www.jcircadianrhythms.com/content/5/1/3

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