Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity

Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity

Adrenal androgens are fundamental mediators of ovarian folliculogenesis, embryonic implantation, and breast development. Although adrenal androgen function in target tissues are well characterized, there is little research covering the role of androgen-signaling within the adrenal itself. Adrenal gl...

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Bibliographic Details
Main Authors: Anne-Louise Gannon, Laura O’Hara, Ian J. Mason, Anne Jørgensen, Hanne Frederiksen, Michael Curley, Laura Milne, Sarah Smith, Rod T. Mitchell, Lee B. Smith
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Endocrinology
Subjects:
adrenal cortex
X-zone
androgen receptor
spindle cell
hyperplasia
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2020.599869/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2020.599869/full

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