A common variant of PNPLA3 (p.I148M) is not associated with alcoholic chronic pancreatitis.

BACKGROUND: Chronic pancreatitis (CP) is an inflammatory disease that in some patients leads to exocrine and endocrine dysfunction. In industrialized countries the most common aetiology is chronic alcohol abuse. Descriptions of associated genetic alterations in alcoholic CP are rare. However, a comm...

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Bibliographic Details
Main Authors: Jonas Rosendahl, Anke Tönjes, Dorit Schleinitz, Peter Kovacs, Johannes Wiegand, Claudia Ruffert, Moritz Jesinghaus, Robert Schober, Max Herms, Robert Grützmann, Hans-Ulrich Schulz, Felix Stickel, Jens Werner, Peter Bugert, Matthias Blüher, Michael Stumvoll, Stephan Böhm, Thomas Berg, Henning Wittenburg, Joachim Mössner, Rene te Morsche, Monique Derikx, Volker Keim, Heiko Witt, Joost P H Drenth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3262779?pdf=render