Spinal cord injury induces upregulation of Beclin 1 and promotes autophagic cell death

Autophagy is a degradation of the cytoplasm and it induces autophagic cell death in several neurodegenerative conditions. Beclin 1, a Bcl-2-interacting protein, is known to be a promoter of autophagy. We investigated the alterations in the Beclin 1 protein expression and the involvement of autophagy...

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Bibliographic Details
Main Authors: Haruo Kanno, Hiroshi Ozawa, Akira Sekiguchi, Eiji Itoi
Format: Article
Language:English
Published: Elsevier 2009-02-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108002179