UPLC/Q-TOFMS-Based Metabolomics Approach to Reveal the Protective Role of Other Herbs in An-Gong-Niu-Huang Wan Against the Hepatorenal Toxicity of Cinnabar and Realgar

UPLC/Q-TOFMS-Based Metabolomics Approach to Reveal the Protective Role of Other Herbs in An-Gong-Niu-Huang Wan Against the Hepatorenal Toxicity of Cinnabar and Realgar

An-Gong-Niu-Huang Wan (AGNH) is a well-known traditional Chinese medicine (TCM) recipe containing cinnabar (HgS) and realgar (As2S2). However, the application of AGNH is limited by the hepato- and nephrotoxicity of cinnabar and realgar. It should be noted that cinnabar and realgar in AGNH are not us...

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Bibliographic Details
Main Authors: Fangbo Xia, Ao Li, Yushuang Chai, Xiao Xiao, Jianbo Wan, Peng Li, Yitao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Pharmacology
Subjects:
An-Gong-Niu-Huang Wan
cinnabar
realgar
metabonomics
detoxification
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00618/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00618/full

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