Synthesis and Biological Evaluation of 2-(3-Fluoro-4-nitro phenoxy)-N-phenylacetamide Derivatives as Novel Potential Affordable Antitubercular Agents

Synthesis and Biological Evaluation of 2-(3-Fluoro-4-nitro phenoxy)-N-phenylacetamide Derivatives as Novel Potential Affordable Antitubercular Agents

A novel series of 2-(3-fluoro-4-nitrophenoxy)-N-phenylacetamide compounds were designed, synthesized and in vitro assessed for their antitubercular activities by a microdilution method. All the novel derivatives exerted potent or moderate active against M. tuberculosis H37Rv, with MIC values ranging...

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Bibliographic Details
Main Authors: Yu-Quan Wei, Tao Yang, Jian-Zhong Yang, Wei-Yi Pi, Ying-Hong Yang, You-Fu Luo, Yong Deng, Yan-Ni Lin, Wei Ang
Format: Article
Language:English
Published: MDPI AG 2012-02-01
Series:Molecules
Subjects:
2-(3-fluoro-4-nitrophenoxy)-N-phenylacetamide
antitubercular
H37Rv
rifampin-resistant
affordable
Online Access:http://www.mdpi.com/1420-3049/17/2/2248/

Internet

http://www.mdpi.com/1420-3049/17/2/2248/

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