Meta-populational demes constitute a reservoir for large MHC allele diversity in wild house mice (Mus musculus)

Meta-populational demes constitute a reservoir for large MHC allele diversity in wild house mice (Mus musculus)

Abstract Background The MHC class I and II loci mediate the adaptive immune response and belong to the most polymorphic loci in vertebrate genomes. In fact, the number of different alleles in a given species is often so large that it remains a challenge to provide an evolutionary model that can full...

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Bibliographic Details
Main Authors: Miriam Linnenbrink, Meike Teschke, Inka Montero, Marie Vallier, Diethard Tautz
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Frontiers in Zoology
Subjects:
Major histocompatibility complex
House mouse
Natural populations
Recombination
Reservoir model
Online Access:http://link.springer.com/article/10.1186/s12983-018-0266-9

Internet

http://link.springer.com/article/10.1186/s12983-018-0266-9

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