Amygdalar Corticotropin-Releasing Factor Signaling Is Required for Later-Life Behavioral Dysfunction Following Neonatal Pain

Neonatal pain such as that experienced by infants in the neonatal intensive care unit is known to produce later-life dysfunction including heightened pain sensitivity and anxiety, although the mechanisms remain unclear. Both chronic pain and stress in adult organisms are known to influence the corti...

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Bibliographic Details
Main Authors: Seth M. Davis, Jared T. Zuke, Mariah R. Berchulski, Michael A. Burman
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Physiology
Subjects:
CRF
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.660792/full