Structure Based Prediction of Neoantigen Immunogenicity

Structure Based Prediction of Neoantigen Immunogenicity

The development of immunological therapies that incorporate peptide antigens presented to T cells by MHC proteins is a long sought-after goal, particularly for cancer, where mutated neoantigens are being explored as personalized cancer vaccines. Although neoantigens can be identified through sequenc...

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Bibliographic Details
Main Authors: Timothy P. Riley, Grant L. J. Keller, Angela R. Smith, Lauren M. Davancaze, Alyssa G. Arbuiso, Jason R. Devlin, Brian M. Baker
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
structure
neoantigen
peptide
MHC
modeling
Rosetta
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02047/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02047/full

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