Cellular and Animal Model Studies on the Growth Inhibitory Effects of Polyamine Analogues on Breast Cancer

Cellular and Animal Model Studies on the Growth Inhibitory Effects of Polyamine Analogues on Breast Cancer

Polyamine levels are elevated in breast tumors compared to those of adjacent normal tissues. The female sex hormone, estrogen is implicated in the origin and progression of breast cancer. Estrogens stimulate and antiestrogens suppress the expression of polyamine biosynthetic enzyme, ornithine decarb...

Full description

Bibliographic Details
Main Authors: T. J. Thomas, Thresia Thomas
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Medical Sciences
Subjects:
polyamines
ornithine decarboxylase
polyamine analogs
spermidine/spermine N1-acetyl transferase
spermine oxidase
bis(ethyl)polyamine analogs
breast cancer
MCF-7 cells
transgenic mice
Online Access:http://www.mdpi.com/2076-3271/6/1/24

Internet

http://www.mdpi.com/2076-3271/6/1/24

Similar Items