Increased Inhibition of the Amygdala by the mPFC may Reflect a Resilience Factor in Post-traumatic Stress Disorder: A Resting-State fMRI Granger Causality Analysis

Increased Inhibition of the Amygdala by the mPFC may Reflect a Resilience Factor in Post-traumatic Stress Disorder: A Resting-State fMRI Granger Causality Analysis

Purpose: To determine whether effective connectivity of the amygdala is altered in traumatized subjects with and without post-traumatic stress disorder (PTSD).Materials and Methods: Resting-state functional MRI data were obtained for 27 patients with typhoon-related PTSD, 33 trauma-exposed controls...

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Bibliographic Details
Main Authors: Feng Chen, Jun Ke, Rongfeng Qi, Qiang Xu, Yuan Zhong, Tao Liu, Jianjun Li, Li Zhang, Guangming Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Psychiatry
Subjects:
post-traumatic stress disorder
amygdala
effective connectivity
medial prefrontal cortex
functional magnetic resonance imaging
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2018.00516/full

Internet

https://www.frontiersin.org/article/10.3389/fpsyt.2018.00516/full

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