Induction of Apoptosis by PQ1, a Gap Junction Enhancer that Upregulates Connexin 43 and Activates the MAPK Signaling Pathway in Mammary Carcinoma Cells

The mechanism of gap junction enhancer (PQ1) induced cytotoxicity is thought to be attributed to the change in connexin 43 (Cx43) expression; therefore, the effects of Cx43 modulation in cell survival were investigated in mammary carcinoma cells (FMC2u) derived from a malignant neoplasm of a female...

Full description

Bibliographic Details
Main Authors: Stephanie N. Shishido, Thu A. Nguyen
Format: Article
Language:English
Published: MDPI AG 2016-01-01
Series:International Journal of Molecular Sciences
Subjects:
PQ1
Online Access:http://www.mdpi.com/1422-0067/17/2/178