Structural Phenotyping of Stem Cell-Derived Cardiomyocytes

Structural phenotyping based on classical image feature detection has been adopted to elucidate the molecular mechanisms behind genetically or pharmacologically induced changes in cell morphology. Here, we developed a set of 11 metrics to capture the increasing sarcomere organization that occurs int...

Full description

Bibliographic Details
Main Authors: Francesco Silvio Pasqualini, Sean Paul Sheehy, Ashutosh Agarwal, Yvonne Aratyn-Schaus, Kevin Kit Parker
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115000417