Transgenic mice with mammary gland targeted expression of human cortactin do not develop (pre-malignant) breast tumors: studies in MMTV-cortactin and MMTV-cortactin/-cyclin D1 bitransgenic mice

Transgenic mice with mammary gland targeted expression of human cortactin do not develop (pre-malignant) breast tumors: studies in MMTV-cortactin and MMTV-cortactin/-cyclin D1 bitransgenic mice

<p>Abstract</p> <p>Background</p> <p>In human breast cancers, amplification of chromosome 11q13 correlates with lymph node metastasis and increased mortality. To date, two genes located within this amplicon, <it>CCND1 </it>and <it>EMS1</it>, were...

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Bibliographic Details
Main Authors: van Krieken Johan HJM, van der Ploeg Jan CM, Schuuring-Scholtes Ellen, van Bragt Maaike PA, van Rossum Agnes GSH, Kluin Philip M, Schuuring Ed
Format: Article
Language:English
Published: BMC 2006-03-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/6/58

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http://www.biomedcentral.com/1471-2407/6/58

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