Hypoxic state and glycolysis as a possible anticancer therapeutic target
In this review the role of hypoxia and glycolysis in tumor expansion is described. Experimental results demonstrate that glycolysis functions in tumor cells are not restrict only energy supply. Glycolysis stimulates the activity of transcription factor HIF-1α. Assemble of HIF1α and protein ARNT stim...
Main Author: | |
---|---|
Format: | Article |
Language: | Russian |
Published: |
ABV-press
2015-06-01
|
Series: | Uspehi Molekulârnoj Onkologii |
Subjects: | |
Online Access: | https://umo.abvpress.ru/jour/article/view/27 |