Inhibition of Hippocampal Matrix Metalloproteinase-3 and -9 Disrupts Spatial Memory
Memory consolidation requires synaptic reconfiguration dependent upon extracellular matrix (ECM) molecules interacting with cell adhesion molecules. Matrix metalloproteinase (MMP) activity is responsible for transient alterations in the ECM that may be prerequisite to hippocampal-dependent learnin...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2007-01-01
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Series: | Neural Plasticity |
Online Access: | http://dx.doi.org/10.1155/2007/73813 |